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1,3-PBIT dihydrobromide

CAS number:200716-66-1    molecular formula:C12H20Br2N4S2

overview

compound introduction

1,3-PBIT is a potent inhibitor of iNOS with a Ki of 47 nM compared to Ki values for eNOS and nNOS are 9 and 0.25 μM, respectively, for the purified human enzymes. Its inhibition in whole cells is greatly diminished, presumably to poor membrane permeability.

Specs

Chinese alias-
English alias-
CAS number200716-66-1molecular formulaC12H20Br2N4S2
molecular weight444.25 g/molExact mass-
PSA-logp-

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