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Senicapoc

CAS number:289656-45-7    molecular formula:C20H15F2NO

overview

compound introduction

Senicapoc(ICA17043)是Gardos通道阻断剂,能抑制钙离子诱导的人血红细胞(RBC)铷流,IC50为11 nM,还能抑制血红细胞(RBC)的脱水,IC50为30 nM. Senicapoc(ICA17043) is a potent and selective Gardos channel blocker; blocked Ca(2+)-induced rubidium flux from human RBCs/ inhibited RBC dehydration with IC50s of 11 nM/30 nM, respectively.

Specs

Chinese alias塞尼卡泊
English alias2,2-bis(4-fluorophenyl)-2-phenylacetamide | A904983 | BBL102413 | DB06280 | GTPL2331 | Senicapoc (USAN) | D06640 | Q65653351 | AKOS007930800 | 4-Methyl-1H-pyrrole-2-carboxylic?acid | UNII-TS6G201A6Q | Senicapoc [USAN:INN] | Bis(4-fluorophenyl)phenylacetam
CAS number289656-45-7molecular formulaC20H15F2NO
molecular weight323.35 g/molExact mass-
PSA43.100 Ųlogp4.1

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