胎球蛋白-A,也称为α-2-HS-糖蛋白(AHSG),由肝脏产生,属于胎球蛋白家族,是一种血浆结合蛋白,在胎儿血液中比成人血液中含量更高。 它参与多种功能,例如内吞作用、大脑发育和骨组织的形成。 胎球蛋白是像白蛋白一样的载体蛋白。 胎球蛋白-A 与钙和磷酸盐形成可溶性复合物,因此是不溶性磷酸钙的载体。 胎球蛋白-A的循环水平可调节细胞依赖性的成骨过程。并可介导某些肿瘤细胞的生长信号。它还可以作为天然抗特定 TGF-β(转化生长因子 β)和 BMP(骨形态发生蛋白)信号蛋白的拮抗剂。血清中胎球蛋白 A 的高水平与轻度成骨不全有关。另外,在佩吉特氏病中观察到它的水平下降。它被预测为下咽鳞状细胞癌早期诊断的潜在生物标志物。
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重组人胎球蛋白A
CAS number:unknown molecular formula:
overview
compound introduction
Specs
| Chinese alias | - | ||
| English alias | alpha 2-Heremans-Schmid glycoprotein(AHSG),Alpha-2-Z-globulin, Ba-alpha-2-glycoprotein | A2HS | AHS | AHSG | alpha-2-HS-glycoprotein | alpha-2-Z-globulin | Ba-alpha-2-glycoprotein | FETUA | Fetuin A | fetuin-A | HSGA | APMR1 | alpha 2-Heremans-Schmid glyc | ||
| CAS number | unknown | molecular formula | |
| molecular weight | - | Exact mass | 无动物源 |
| PSA | - | logp | - |
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