CAS number：1997369-78-4(DMSO) molecular formula：C28H35F2N5O3
GSK8814 is a potent, selective, and ATAD2/2B bromodomain chemical probe and inhibitor, with a binding constant pK d =8.1 and a pK i =8.9 in BROMOscan. GSK8814 binds to ATAD2 and BRD4 BD1 with pIC 50 s of 7.3 and 4.6, respectively. GSK8814 shows 500-fold selectivity for ATAD2 over BRD4 BD1 IC50& Target:ATAD2 8.9 (pKi) ATAD2 8 nM (Ki) BRD4 BD1 4.6 (pIC 50 )
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| CAS number | 1997369-78-4(DMSO) | molecular formula | C28H35F2N5O3 |
| molecular weight | 527.61 g/mol | Exact mass | 10mM in DMSO |
| PSA | - | logp | - |
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