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Samatasvir

CAS number:1312547-19-5    molecular formula:C47H48N8O6S2

overview

compound introduction

Samatasvir (IDX71) is a potent, orally active NS5A inhibitor of HCV replication. Samatasvir is effective and selective against infectious HCV and replicons, with EC 50 s falling within a tight range of 2 to 24 pM in genotype 1 through 5 replicons. In Vitro Samatasvir (IDX719) retains full activity in the presence of HIV and hepatitis B virus (HBV) antivirals and is not cross-resistant with HCV protease, nucleotide, and nonnucleoside polymerase inhibitor classes. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid

Specs

Chinese alias萨马他韦
English aliasSamatasvir | HY-16784 | SAMATASVIR [INN] | Carbamic acid, N-((1R)-2-((2S)-2-(5-(4-(6-(2-((2S)-1-((2S)-2-((methoxycarbonyl)amino)-3-methyl-1-oxobutyl)-2-pyrrolidinyl)-1H-benzimidazol-6-yl)thieno(3,2-b)thien-3-yl)phenyl)-1H-imidazol-2-yl)-1-pyrrolidinyl)-2-
CAS number1312547-19-5molecular formulaC47H48N8O6S2
molecular weight885.06 g/molExact mass-
PSA231.000 Ųlogp7.6

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