Samatasvir (IDX71) is a potent, orally active NS5A inhibitor of HCV replication. Samatasvir is effective and selective against infectious HCV and replicons, with EC 50 s falling within a tight range of 2 to 24 pM in genotype 1 through 5 replicons. In Vitro Samatasvir (IDX719) retains full activity in the presence of HIV and hepatitis B virus (HBV) antivirals and is not cross-resistant with HCV protease, nucleotide, and nonnucleoside polymerase inhibitor classes. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid
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Samatasvir
CAS number:1312547-19-5 molecular formula:C47H48N8O6S2
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| Chinese alias | 萨马他韦 | ||
| English alias | Samatasvir | HY-16784 | SAMATASVIR [INN] | Carbamic acid, N-((1R)-2-((2S)-2-(5-(4-(6-(2-((2S)-1-((2S)-2-((methoxycarbonyl)amino)-3-methyl-1-oxobutyl)-2-pyrrolidinyl)-1H-benzimidazol-6-yl)thieno(3,2-b)thien-3-yl)phenyl)-1H-imidazol-2-yl)-1-pyrrolidinyl)-2- | ||
| CAS number | 1312547-19-5 | molecular formula | C47H48N8O6S2 |
| molecular weight | 885.06 g/mol | Exact mass | - |
| PSA | 231.000 Ų | logp | 7.6 |
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