Substance P(1-7) TFA is a fragment of the neuropeptide, substance P (SP). Substance P(1-7) TFA gives depressor and bradycardic effects when applied to the nucleus tractus solitarius. In Vivo Substance P(1-7) is found to act as a very potent antagonist against the SP-induced responses and is formed locally in the nigra after SP injection. It is proposed that Substance P(1-7) is an endogenous modulator of SP actions . Injection of low doses of Substance P(1-7) (1.0-4.0 pM simultaneously with SP or SP(5-11) (0.1 nM), reduce aversive behaviours induced by SP or SP(5- 11) significantly. These results indicate that SP(1-7) formed endogenously could modulate the actions of SP or SP(5-11) in the spinal cord. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid
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Substance P(1-7) TFA
CAS number：2828433-22-1 molecular formula：C43H66F3N13O12
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| Chinese alias | - | ||
| English alias | - | ||
| CAS number | 2828433-22-1 | molecular formula | C43H66F3N13O12 |
| molecular weight | 1014.06 g/mol | Exact mass | ≥99% |
| PSA | - | logp | - |
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