compound introduction
NCGC00029283 is a werner syndrome helicase-nuclease (WRN) helicase inhibitor with IC 50 s of 2.3 μM, 12.5 μM, and 3.4 μM for WRN, BLM and FANCJ helicase, respectively. In Vitro NCGC00029283 (0-100 μM; 24-72 h) effectively blocks cell proliferation in U2-OS cells. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Cell Proliferation AssayCell Line: U2-OS cells Concentration: 1 μM, 10 μM, 100 μM Incubation Time: 24 h, 48 h, 72 h Result: Showed a reduction in U2-OS cell proliferation.
