BMS-433771 dihydrochloride hydrate is a potent orally active inhibitor of respiratory syncytial virus (RSV) . BMS-433771 dihydrochloride hydrate is active against both A and B groups of RSV , with an average EC 50 of 20 nM. BMS-433771 dihydrochloride hydrate can be used for the research of respiratory tract disease In Vitro BMS-433771 dihydrochloride hydrate has inhibitory against both A and B groups of RSV, with an average EC 50 of 20 nM. BMS-433771 dihydrochloride hydrate can inhibit viral F protein-induced membrane fusion. MCE has not independently confirmed the accuracy of these methods. They are for reference only. In Vivo BMS-433771 dihydrochloride hydrate (p.o.; 1-200 mg/kg; single or bid 4 days) shows prophylactic efficacy via oral dosing，but has considerable pharmacodynamic differences between the two rodent models. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid IC50& Target:EC50: 20 nM (RSV)
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BMS-433771 dihydrochloride hydrate
CAS number：543700-67-0 molecular formula：C21H27Cl2N5O3
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| Chinese alias | BMS-433771 二盐酸盐水合物 | ||
| English alias | - | ||
| CAS number | 543700-67-0 | molecular formula | C21H27Cl2N5O3 |
| molecular weight | 468.38 g/mol | Exact mass | ≥98% |
| PSA | - | logp | - |
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