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MM-401 TFA

CAS number:1442106-11-7    molecular formula:C31H47F3N8O7

overview

compound introduction

MM-401 (TFA) is a MLL1 H3K4 methyltransferase inhibitor. MM-401 inhibits MLL1 activity ( IC 50 = 0.32 µM) by blocking MLL1-WDR5 interaction. MM-401 can induce cell cycle arrest, apoptosis and differentiation. MM-401 can be used for the research of MLL leukemia In Vitro MM-401 maintains high binding affinity to WDR5 with a K i value of Form:Solid IC50& Target:Ki:

Specs

Chinese aliasMM-401 三氟乙酸
English alias-
CAS number1442106-11-7molecular formulaC31H47F3N8O7
molecular weight700.75 g/molExact mass≥99%
PSA-logp-

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