MM-401 (TFA) is a MLL1 H3K4 methyltransferase inhibitor. MM-401 inhibits MLL1 activity ( IC 50 = 0.32 µM) by blocking MLL1-WDR5 interaction. MM-401 can induce cell cycle arrest, apoptosis and differentiation. MM-401 can be used for the research of MLL leukemia In Vitro MM-401 maintains high binding affinity to WDR5 with a K i value of Form:Solid IC50& Target:Ki:
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MM-401 TFA
CAS number:1442106-11-7 molecular formula:C31H47F3N8O7
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| Chinese alias | MM-401 三氟乙酸 | ||
| English alias | - | ||
| CAS number | 1442106-11-7 | molecular formula | C31H47F3N8O7 |
| molecular weight | 700.75 g/mol | Exact mass | ≥99% |
| PSA | - | logp | - |
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