compound introduction
hMAO-B-IN-4 (compound B10) is a selective, reversible and blood–brain barrier (BBB) penetrable human monoamine oxidase-B ( hMAO-B ) inhibitor with an IC 50 value and a K i value of 0.067 and 0.03 μM, respectively. hMAO-B-IN-4 inhibits hMAO-A with an IC 50 value of 33.82 μM. hMAO-B-IN-4 can be used for Alzheimer’s disease (AD) and Parkinson’s disease (PD) research. In Vitro hMAO-B-IN-4 (0-40 μM) shows high selectivity to hMAO-B than hMAO-A with a SI value of 504.791. hMAO-B-IN-4 (0-40 μM) inhibits hMAO-A and hMAO-B with IC 50 values of 33.821 and 0.067 μM, respectively. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid
