Urotensin II (114-124), human TFA, an 11-amino acid residue peptide, is a potent vasoconstrictor and agonist for the orphan receptor GPR14 . Appearance:Solid IC50& Target:GPR14 In Vitro:Human Urotensin II (U-II) binds to recombinant human GPR14 with high affinity, and the binding is functionally coupled to calcium mobilization. Human Urotensin II induces concentration-dependent increases in intracellular calcium in a HEK-293 cell line ex In Vivo:Human Urotensin II (U-II) markedly increases total peripheral resistance in anaesthetized non-human primates, a response associated with profound cardiac contractile dysfunction. MCE has not independently confirmed the accuracy of these methods. They Biological Activity:Urotensin II (114-124), human TFA, an 11-amino acid residue peptide, is a potent vasoconstrictor and agonist for the orphan receptor GPR14 .
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Urotensin II (114-124), human TFA
CAS number:unknown molecular formula:C66H86F3N13O20S2
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| Chinese alias | 尾加压素 II (114-124),人类 TFA | ||
| English alias | - | ||
| CAS number | unknown | molecular formula | C66H86F3N13O20S2 |
| molecular weight | 1502.59 g/mol | Exact mass | - |
| PSA | - | logp | - |
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