RA375 is a RPN13 (26S proteasome regulatory subunit) inhibitor. RA375 activates UPR signaling, ROS production and apoptosis . RA375 exhibits ten-fold greater activity against cancer lines than RA190, reflecting its nitro ring substituents and the addition Appearance:Solid In Vivo:RA375 (10mg/kg, ip) inhibits proteasome function and reduces ovarian tumor burden in mice. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Animal Model: RA375 (10mg/kg, ip) inhibits proteasome functio Biological Activity:RA375 is a RPN13 (26S proteasome regulatory subunit) inhibitor. RA375 activates UPR signaling, ROS production and apoptosis . RA375 exhibits ten-fold greater activity against cancer lines than RA190, reflecting its nitro ring substituents and the addition
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RA375
CAS number：unknown molecular formula：C30H25ClN4O7
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compound introduction
Specs
| Chinese alias | - | ||
| English alias | - | ||
| CAS number | unknown | molecular formula | C30H25ClN4O7 |
| molecular weight | 589 g/mol | Exact mass | ≥99% |
| PSA | - | logp | - |
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