MS31 trihydrochloride is a potent, highly affinity and selective fragment-like methyllysine reader protein spindlin 1 (SPIN1) inhibitor. MS31 trihydrochloride potently inhibits the interactions between SPIN1 and H3K4me3 ( IC 50 =77 nM, AlphaLISA; 243 nM, IC50& Target:IC50: 77 nM (SPIN1 by AlphaLISA), 243 nM (SPIN1 by FP) Kd: 91 nM (SPIN1) In Vitro:MS31 trihydrochloride potently inhibits binding of trimethyllysine-containing peptides to SPIN1, displays high binding affinity, is highly selective for SPIN1 over other epigenetic readers and writers, directly engages SPIN1 in cells, and is not toxic to Biological Activity:MS31 trihydrochloride is a potent, highly affinity and selective fragment-like methyllysine reader protein spindlin 1 (SPIN1) inhibitor. MS31 trihydrochloride potently inhibits the interactions between SPIN1 and H3K4me3 ( IC 50 =77 nM, AlphaLISA; 243 nM,
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MS31 trihydrochloride
CAS number：unknown molecular formula：C20H30Cl3N3O2
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| Chinese alias | MS31 三盐酸盐 | ||
| English alias | - | ||
| CAS number | unknown | molecular formula | C20H30Cl3N3O2 |
| molecular weight | 450.83 g/mol | Exact mass | 10mM in DMSO |
| PSA | - | logp | - |
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