Orexin B, human (TFA) is an endogenous agonist at Orexin receptor with K i s of 420 and 36 nM for OX1 and OX2, respectively. Appearance:Solid IC50& Target:Ki: 420 nM (OX1), 36 nM (OX2) . In Vitro:Orexin B is derived by proteolytic amino acid precursor, prepro-orexin, which is encoded by a gene localized to chromosome 17q21 in humans. In radioligand binding studies, Orexin B has a higher affinity for the OX2 receptor. Human Orexin B has two am In Vivo:Human Orexin B significantly augments food intake; at the 2 hr time point, 5- and 12-fold stimulation of food consumption is observed by 3 nM and 30 nM orexin-B, respectively. MCE has not independently confirmed the accuracy of these methods. They ar Biological Activity:Orexin B, human (TFA) is an endogenous agonist at Orexin receptor with K i s of 420 and 36 nM for OX1 and OX2, respectively.
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Orexin B, human TFA
CAS number：unknown molecular formula：C123H212N44O35S.C2HF3O2
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compound introduction
Specs
| Chinese alias | Orexin B，人类 TFA | ||
| English alias | - | ||
| CAS number | unknown | molecular formula | C123H212N44O35S.C2HF3O2 |
| molecular weight | 3013.36 g/mol | Exact mass | ≥98% |
| PSA | - | logp | - |
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