OTS186935 hydrochloride is a potent protein methyltransferase SUV39H2 inhibitor with an IC 50 of 6.49 nM. OTS186935 hydrochloride shows significant inhibition of tumor growth in mouse xenograft models without any detectable toxicity. OTS193320 hydrochlori Appearance:Solid IC50& Target:IC50: 6.49 nM (SUV39H2) In Vitro:OTS186935 hydrochloride inhibits A549 cell growth with an IC 50 of 0.67 μM. MCE has not independently confirmed the accuracy of these methods. They are for reference only. In Vivo:OTS186935 hydrochloride (10mg/kg or 25mg/kg; intravenously; once daily for 14 days) exhibits growth suppressive effects in human cancer cell line derived xenograft models. MCE has not independently confirmed the accuracy of these methods. They are Biological Activity:OTS186935 hydrochloride is a potent protein methyltransferase SUV39H2 inhibitor with an IC 50 of 6.49 nM. OTS186935 hydrochloride shows significant inhibition of tumor growth in mouse xenograft models without any detectable toxicity. OTS193320 hydrochlori
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OTS186935 hydrochloride
CAS number：unknown molecular formula：C25H26ClN5O2.8/5HCl
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| Chinese alias | OTS186935 盐酸盐 | ||
| English alias | - | ||
| CAS number | unknown | molecular formula | C25H26ClN5O2.8/5HCl |
| molecular weight | 522.31 g/mol | Exact mass | ≥99% |
| PSA | - | logp | - |
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