序列：{Eicosanedioic acid-γ-Glu}-Lys-Cys-Asn-Thr-Ala-Thr-Cys-Ala-Thr-Gln-Arg-Leu-Ala-Glu-Phe-Leu-Arg-His-Ser-Ser-Asn-Asn-Phe-Gly-Pro-Ile-Leu-Pro-Pro-Thr-Asn-Val-Gly-Ser-Asn-Thr-Pro-NH2 (Disulfide bridge:Cys3-Cys8) Cagrilintide acetate is a non-selective AMYR/CTR agonist and long-acting acylated amylase analogue. Cagrilintide acetate causes a reduction in food intake and significant weight loss in a dose-dependent manner. Cagrilintide acetate can be used in obesity Appearance:Solid IC50& Target:AMYR, CTR . In Vivo:Cagrilintide acetate (compound 23) (0.1, 1, 3, 10, 30 nmol/kg; s.c.single) reduces food intake in the rat. Cagrilintide acetate (10 nmol/kg; i.v. or s.c.; single) shows good pharmacokinetic parameters. MCE has not independently confirmed the acc Biological Activity:Cagrilintide acetate is a non-selective AMYR/CTR agonist and long-acting acylated amylase analogue. Cagrilintide acetate causes a reduction in food intake and significant weight loss in a dose-dependent manner. Cagrilintide acetate can be used in obesity
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Cagrilintide acetate
CAS number：1415456-99-3(free base) molecular formula：C194H312N54O59S2(free base)
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| Chinese alias | 卡格林肽醋酸盐 | ||
| English alias | - | ||
| CAS number | 1415456-99-3(free base) | molecular formula | C194H312N54O59S2(free base) |
| molecular weight | 4409.01(free base) g | Exact mass | ≥98% |
| PSA | - | logp | - |
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