CAS number：740816-86-8 molecular formula：C34H28N4O4
O-Desmethyl Midostaurin (CGP62221; O-Desmethyl PKC412) is the active metabolite of Midostaurin via cytochrome P450 liver enzyme metabolism. O-Desmethyl Midostaurin can be used as an indicator for Midostaurin metabolism in vivo Midostaurin is a multi-targeted protein kinase inhibitor with IC 50 ranging from 22-500 nM. Form:Solid IC50& Target:IC50: active metabolite of Midostaurin
| Chinese alias | O-去甲基米哚妥林 | ||
| English alias | CGP62221 | CGP-62221 | O-Desmethyl Midostaurin | o-Desmethyl-pkc 412 | UNII-H3W3QJ5C7G | H3W3QJ5C7G | N-((9S,10R,11R,13R)-2,3,10,11,12,13-Hexahydro-10-hydroxy-9-methyl-1-oxo-9,13-epoxy-1H,9H-diindolo(1,2,3-gh:3',2',1'-lm)pyrrolo(3,4-j)(1,7)benzodiazonin-1 | ||
| CAS number | 740816-86-8 | molecular formula | C34H28N4O4 |
| molecular weight | 556.61 g/mol | Exact mass | - |
| PSA | - | logp | - |
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