CAS number：174064-08-5 molecular formula：C18H14KNO3
Oxaprozin potassium is an orally active and potent inhibitor of COX, with IC 50 values of 2.2 μM and 36 μM for human platelet COX-1 and for IL-1-stimulated human synovial cell COX-2, respectively. Oxaprozin potassium induces cell apoptosis. Oxaprozin potassium also inhibits the NF-κB activation. Oxaprozin potassium-mediated inhibition of the Akt/IKK/NF-κB pathway contributes to its anti-inflammatory properties
| Chinese alias | 恶丙嗪钾 | ||
| English alias | CHEMBL1200463 | 4,5-Diphenyl-2-oxazolepropanoic Acid, Potassium Salt | OXAPROZIN POTASSIUM [WHO-DD] | HY-B0808A | SCHEMBL8190699 | DTXCID0092245 | Q27284098 | OXAPROZIN POTASSIUM [ORANGE BOOK] | 3-(4,5-diphenyl-1,3-oxazol-2-yl)propanoate | potassium | ||
| CAS number | 174064-08-5 | molecular formula | C18H14KNO3 |
| molecular weight | 331.4 g/mol | Exact mass | ≥95% |
| PSA | - | logp | - |
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