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Complement C5-IN-1

CAS number:2365402-67-9(DMSO)    molecular formula:C24H32N2O6

overview

compound introduction

Complement C5-IN-1 (Compound 7) is a small-molecule inhibitor of complement component 5 protein ( C5 ). Complement C5-IN-1 interacts with C5 to prevent its cleavage by the C5 convertase and blocks zymosan-induced the membrane-attack complex (MAC) deposition in 50% human whole blood with an IC 50 of 0.77 µM.

Specs

Chinese alias-
English alias-
CAS number2365402-67-9(DMSO)molecular formulaC24H32N2O6
molecular weight444.52 g/molExact mass10mM in DMSO
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