compound introduction
FGFR3-IN-5 is a potent and selective FGFR3 inhibitor with IC 50 values of 3, 44, and 289 nM for FGFR3 , FGFR2 , and FGFR1 , respectively. FGFR3-IN-5 can be used in research of cancer In Vitro FGFR3-IN-5 (compound 37; 5 mM; 1 h; HEK-293 cells) inhibits FGFR phosphorylation with IC 50 values of 8 and 59 nM for FGFR3 and FGFR1, respectively. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid IC50& Target:FGFR3 3 nM (IC 50 ) FGFR2 44 nM (IC 50 ) FGFR1 289 nM (IC 50 )
