CAS number：823828-18-8 molecular formula：C19H15NO7S2
C188 is a STAT3 inhibitor that inhibits IL-6-stimulated STAT3 phosphorylation and nuclear translocation in HepG2 cells by targeting STAT3 SH2 domain peptide-binding pocket. C188, in particular, was highly active in inducing apoptosis of the breast cancer cell line MB-MDA-468 in vitro ( EC 50 = 0.7 μM). Form:Solid
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| English alias | - | ||
| CAS number | 823828-18-8 | molecular formula | C19H15NO7S2 |
| molecular weight | 433.45 g/mol | Exact mass | - |
| PSA | - | logp | - |
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