compound introduction
N-(m-PEG4)-N'-(DBCO-PEG4)-Cy5 是一种 PROTAC linker，属于 PEG 类。可用于合成 PROTAC 分子。N-(m-PEG4)-N'-(DBCO-PEG4)-Cy5 是一种点击化学试剂。它含有 DBCO 基团，可以和含有 Azide 基团的分子发生环张力 (strain) 促进的炔-叠氮环加成反应 (SPAAC)。 Extinction Coefficient Excitation Maximum: 107000; N-(m-PEG4)-N'-(DBCO-PEG4)-Cy5 is a Cy5 labeled fluorescent PEG derivative containinig DBCO group, which reacts with azide-bearing compounds or biomolecules to form a stable triazole linkage without copper catalyst. DBCO-activated fluorescein dye will be an ideal alternative to copper intolerant applications. The hydrophilic PEG spacer increases solubility in aqueous media.
