DBCO-PEG4-NH-Boc 是一种 PROTAC linker,属于 PEG 类。可用于合成 PROTAC 分子。DBCO-PEG4-NH-Boc 是一种点击化学试剂。它含有 DBCO 基团,可以和含有 Azide 基团的分子发生环张力 (strain) 促进的炔-叠氮环加成反应 (SPAAC)。 DBCO-PEG4-NH-Boc is a PEG derivative with a DBCO group and a Boc-protected amine. The DBCO can undergo copper-free Click Chemistry reactions with azides. The Boc protecting group can be removed under acidic conditions to further react. The hydrophilic PEG linker increases the water solubility of the compound. DBCO-PEG4-NH-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. DBCO-PEG4-NH-Boc is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
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DBCO-PEG4-NH-Boc
CAS number:2353410-17-8 molecular formula:C34H45N3O8
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| Chinese alias | - | ||
| English alias | - | ||
| CAS number | 2353410-17-8 | molecular formula | C34H45N3O8 |
| molecular weight | 623.74 g/mol | Exact mass | ≥98% |
| PSA | - | logp | - |
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