compound introduction
m-PEG4-DBCO 是一种 PROTAC linker，属于 PEG 类。可用于合成 PROTAC 分子。m-PEG4-DBCO 是一种点击化学试剂。它含有 DBCO 基团，可以和含有 Azide 基团的分子发生环张力 (strain) 促进的炔-叠氮环加成反应 (SPAAC)。 m-PEG4-DBCO is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. m-PEG4-NH-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. m-PEG4-DBCO is a DBCO-activated reagents and can react with azides via a copper-free Click Chemistry reaction to form a stable triazole. This reagent can be applied to situations when copper is a concern for DBCO-activated PEGylation.
