描述及优势 • 提供1136种靶向G蛋白偶联受体的小分子，可用于高通量筛选和高内涵筛选 • GPCR化合物库中的所有小分子都具有良好的生物和药学活性 • 一项发现GPCR药物是最丰富信号受体的有力工具 • 据估计大约200个“孤儿”GPCR功能是未知的，因此，使用我们的GPCR小分子化合物库来筛选功能未知的GPCR可能会产生潜在的新型GPCR候选药 • GPCR化合物库含有与受体相关的小分子， 包括5-HT 受体、多巴胺受体、阿片受体、肾上腺素受体、大麻素受体、mGluR和 ETA-受体等 • 结构多样，药效显著，可渗透细胞 • 具有充分详细的结构说明及客户反馈资料 • NMR和HPLC技术保证产品高纯度 详细信息 配制 1035个化合物预溶于10mM DMSO，67个化合物预溶于10mM水,30个化合物预溶于2mM DMSO，4个化合物预溶于2mM水 容器 带有螺旋盖和二维码的96孔储存管 储存条件 1年 -20°C溶于DMSO 2年 -80°C溶于DMSO •A unique collection of 1136 small molecules targeting G protein coupled receptors for high throughput screening (HTS) and high content screening (HCS) • All of the small molecules in the GPCR library are well characterized with biological and pharmaceutical activity • A powerful tool for discovering GPCR-based drugs that are the richest signal receptor targets for drug discovery • It is estimated about 200 so-called orphan GPCRs are functionally unknown, as a result, use of our GPCR Small Molecule Compound Library for screening the functionally unknown GPCRs may yield potentially new GPCR-based drug candidates • The GPCR compound library contains small molecules associated with receptors including 5-HT Receptor, Dopamine Receptor, Opioid Receptor, Adrenergic Receptors, Cannabinoid Receptor, mGluR, and ETA-receptor etc. • Structurally diverse, medicinally active, and cell permeable • Rich documentation with structure and customer reviews • NMR and HPLC validated to ensure the highest purity Product Details Formulation 1035 compounds pre-dissolved in 10mM DMSO，67 compounds pre-dissolved in 10mM H2O,30 compounds pre-dissolved in 2mM DMSO，4 compounds pre-dissolved in 2mM H2O Container 96 Well Format Sample Storage Tube With Screw Cap and Optional 2D Barcode Stability 12 months -20°C in DMSO 24 months -80°C in DMSO GPCR Compound Library Composition
All
Chemical Reagents
Biomedicine
Organic raw materials
Inorganic chemical industry
intermediate
Agricultural chemicals
Auxiliaries and catalysts
Fragrances and Flavors
Dyes and Pigments
Daily chemical industry
GPCR Compound Library
CAS number：unknown molecular formula：
overview
compound introduction
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