CAS number：793719-01-4 molecular formula：C11H13ClN2O3S
EN450 是一种针对的 NF-κB 的半胱氨酸反应性共价分子胶降解剂，具有抗增殖活性和潜在的抗癌活性，通过依赖Cullin E3 连接酶和蛋白酶发挥作用，可用于研究白血病。 EN450 is a cysteine-responsive covalent molecular gel degrader of targeted NF-κB with antiproliferative and potentially anticancer activity, which acts through a dependence on Cullin E3 ligase and protease, and can be used to study leukemia.
| Chinese alias | EN-450 | ||
| English alias | N-(2-Chloro-5-(N,N-dimethylsulfamoyl)phenyl)acrylamide | ||
| CAS number | 793719-01-4 | molecular formula | C11H13ClN2O3S |
| molecular weight | 288.75 g/mol | Exact mass | - |
| PSA | 74.900 Ų | logp | 1.300 |
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