compound introduction
PROTAC BRD9 Degrader-1 is a PROTAC connected by ligands for Cereblon and BRD9 ( IC 50 =13.5 nM), which can be used as a selective probe useful for the study of BAF complex biology In Vitro PROTAC BRD9 Degrader-1 (Compound 1) inhibits BRD9, BRD4, and CRBN-DDB1 with IC 50 s of 13.5 nM, 3.78 μM, and 48.9 nM, respectively. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid IC50& Target:BRD9 13.5 nM (IC 50 ) BRD4 3.78 μM (IC 50 ) CRBN-DDB1 48.9 nM (IC 50 )
