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PROTAC BET Degrader-10

CAS number:1957234-97-7(DMSO)    molecular formula:C39H39ClN8O6S

overview

compound introduction

PROTAC BET Degrader-10 is a potent BET protein BRD4 degrader extracted from patent WO2017007612A1, example 37, connected by ligands for Cereblon and BRD4 , with a DC 50 of 49 nM.

Specs

Chinese aliasPROTAC BET 降解剂-10
English alias-
CAS number1957234-97-7(DMSO)molecular formulaC39H39ClN8O6S
molecular weight783.29 g/molExact mass10mM in DMSO
PSA-logp-

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