compound introduction
m-PEG-mal (MW 2000) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. Appearance:Solid IC50& Target:PEGs In Vitro:PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. MCE Biological Activity:m-PEG-mal (MW 2000) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
