CAS number：2785323-62-6 molecular formula：C29H29ClN6O5S
PROTAC-O4I2 是一种靶向剪接因子 3B1 (SF3B1) 的 PROTAC。PROTAC-O4I2 在 K562 细胞中诱导 FLAG-SF3B1 降解，IC50 值为 0.244 μM。PROTAC-O4I2 还诱导 K562 WT 细胞凋亡 (apoptosis)。 PROTAC-O4I2 is a PROTAC targets splicing factor 3B1 (SF3B1). PROTAC-O4I2 induces FLAG-SF3B1 degradation with an IC50 value of 0.244 μM in K562 cells. PROTAC-O4I2 also induces cellular apoptosis in K562 WT cells
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| CAS number | 2785323-62-6 | molecular formula | C29H29ClN6O5S |
| molecular weight | 609.10 g/mol | Exact mass | - |
| PSA | - | logp | - |
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