Asundexian (BAY 2433334) 是一种口服活性凝血因子 FXIa 抑制剂。Asundexian 直接、有效、可逆地结合 FXIa 的活性位点,从而抑制其活性。Asundexian 抑制缓冲液中的人 FXIa 的 IC50 为 1 nM。 Asundexian (BAY 2433334) is an orally active coagulation factor Xia (FXIa) inhibitor. Asundexian binds directly, potently, and reversibly to the active site of FXIa and thereby inhibits its activity. Asundexian inhibits human FXIa in buffer with an IC50 of 1 nM.
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asundexian
CAS number:2064121-65-7 molecular formula:C26H21ClF4N6O4
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| Chinese alias | 阿松德西安 | ||
| English alias | BAY-2433334 | ||
| CAS number | 2064121-65-7 | molecular formula | C26H21ClF4N6O4 |
| molecular weight | 592.93 g/mol | Exact mass | - |
| PSA | 132.000 Ų | logp | 3.000 |
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