FABP5-IN-1 is a selective and high affinity fatty acid binding protein 5 (FABP5) inhibitor with a K i value of 1.7 μM, and does not bind to both FABP3 and FABP7. FABP5-IN-1 shows potent antinociceptive effects In Vivo FABP5-IN-1 (Compounds 4j; 20 mg/kg; intraperitoneal injection; for 90 minutes; male wild-type C57BL/6 mice) treatment displays potent antinociceptive effects in CFA model . MCE has not independently confirmed the accuracy of these methods. They are for reference only. Animal Model: Male wild-type C57BL/6 mice injected with complete Freund’s adjuvant (CFA) Dosage: 20 mg/kg Administration: Intraperitoneal injection; for 90 minutes Result: Displayed potent antinociceptive effects in CFA model. Form:Solid IC50& Target:Ki: 1.7 μM (FABP5)
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FABP5-IN-1
CAS number：2132990-98-6 molecular formula：C34H30O6
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| Chinese alias | - | ||
| English alias | - | ||
| CAS number | 2132990-98-6 | molecular formula | C34H30O6 |
| molecular weight | 534.60 g/mol | Exact mass | ≥98% |
| PSA | - | logp | - |
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