compound introduction
AF38469 is a selective, orally bioavailable Sortilin inhibitor with an IC 50 value of 330 nM. In Vivo AF38469 (1 mg/kg; i.v.) has a low volume of distribution (blood volume of 0.7 L/kg) and low clearance (4.8 L/h/kg), and a half-life (t1/2) of 1.2 h in rat . MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid IC50& Target:IC50:330 nM (Sortilin)
