ent-Tadalafil (ent-IC-351), compound (6S,12aS), is a inactive cis-enantiomer of compound (6R,12aS). compound (6R,12aS) is a potent PDE5 inhibitor with an IC 50 of 0.090 μM, while ent-Tadalafil is inactive at concentrations up to 10 µM Form:Solid IC50& Target:PDE5 10 μM (IC 50 )
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ent-Tadalafil
CAS number:629652-72-8 molecular formula:C22H19N3O4
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compound introduction
Specs
| Chinese alias | 恩他达拉非 | ||
| English alias | (5S,6S)-6-Benzo[1,3]dioxol-5-yl-2-methyl-2,3,6,7,12,12a-hexahydro-pyrazino[1'',2'':1,6]pyrido[3,4-b]indole-1,4-dione | Tadalafil, (6S ,12aS)- | SCHEMBL7440401 | TADALAFIL IMPURITY B [EP IMPURITY] | (-)-TRANS-TADALAFIL | Tadalafil 6S ,12as enantiomer | (2S | ||
| CAS number | 629652-72-8 | molecular formula | C22H19N3O4 |
| molecular weight | 389.40 g/mol | Exact mass | ≥98% |
| PSA | 74.900 Ų | logp | 2.300 |
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