DFP00173 is a potent and selective aquaporin-3 (AQP3) inhibitor. DFP00173 inhibits mouse and human AQP3 with an IC 50 of ∼0.1-0.4 μM. DFP00173 is selective for AQP3 over the homologous AQP isoforms AQP7 and AQP9. In Vitro DFP00173 inhibits the glycerol permeability of human erythrocytes with an IC 50 of ~0.2 µM. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid
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DFP00173
CAS number:672286-03-2 molecular formula:C11H7Cl2N3O3S
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| Chinese alias | - | ||
| English alias | DTXSID701329723 | N-(2,6-dichlorophenyl)-N'-(5-nitro-3-thienyl)urea | MLS000851390 | CCG-242921 | AKOS040732960 | HY-126073 | MS-24996 | SMR000457833 | HMS2783C13 | DFP00173 | 1-(2,6-dichlorophenyl)-3-(5-nitrothiophen-3-yl)urea | ||
| CAS number | 672286-03-2 | molecular formula | C11H7Cl2N3O3S |
| molecular weight | 332.16 g/mol | Exact mass | ≥99% |
| PSA | 115.000 Ų | logp | 3.600 |
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