compound introduction
nAChR agonist 1 是一种有效的、脑通透性强的、口服有效的 α7 烟碱乙酰胆碱受体 (α7 nicotinic acetylcholine receptor) 的正向变构调节剂。nAChR agonist 1 在 Ca2+ 中，对内源性表达 α7 nAChR 的人 IMR-32 神经母细胞瘤细胞的 EC50 为 0.32 μM。nAChR agonist 1 可用于阿尔茨海默病的研究。
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DUN71755
CAS number：1394371-75-5 molecular formula：C20H18ClNO3S2
overview
Specs
| Chinese alias | - | ||
| English alias | MFCD32671353 | DUN71755 | 4-[5-(4-Chlorophenyl)-4-methyl-2-(1-oxopropyl)-3-thienyl]benzenesulfonamide | nAChR agonist 1(DUN71755) | BDBM50514307 | DTXSID801142748 | 4-[5-(4-chlorophenyl)-4-methyl-2-propanoylthiophen-3-yl]benzenesulfonamide | MS-27363 | DU | ||
| CAS number | 1394371-75-5 | molecular formula | C20H18ClNO3S2 |
| molecular weight | 419.95 g/mol | Exact mass | ≥98% |
| PSA | 114.000 Ų | logp | 4.900 |
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