compound introduction
RL648_81 是一种特异性的 KQT 样亚家族 2/3 (KCNQ2/3) 激活剂，EC50为 190 nM。RL648_81 有效地将 KCNQ2/3 通道的 V1/2 转移到超极化电位，而对 KCNQ4 或 KCNQ5 没作用。RL648_81 具有与神经元过度兴奋相关的神经系统疾病潜力的研究。
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ethyl N-[2-amino-3-fluoro-4-[[4-(trifluoromethyl)phenyl]methylamino]phenyl]carbamate
CAS number：1919050-87-5 molecular formula：C17H17F4N3O2
overview
Specs
| Chinese alias | - | ||
| English alias | - | ||
| CAS number | 1919050-87-5 | molecular formula | C17H17F4N3O2 |
| molecular weight | 371.33 g/mol | Exact mass | ≥99% |
| PSA | 76.400 Ų | logp | 3.700 |
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