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Crobenetine

CAS number:221019-25-6    molecular formula:C25H33NO2

overview

compound introduction

Crobenetine (BIII-890) 是一种苯并吗喃衍生物,一种有效、选择性且高度依赖的Na+通道阻滞剂。Crobenetine 在大鼠脑突触体中取代 Na+通道位点 2 的[3H]BTX (IC50=49 nM),但对 其他受体和离子通道仅表现出较低的结合亲和力。Crobenetine 可保护啮齿动物的脑组织免受局灶性脑缺血的有害影响。

Specs

Chinese alias-
English alias-
CAS number221019-25-6molecular formulaC25H33NO2
molecular weight379.500 g/molExact mass-
PSA32.700 Ųlogp5.400

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