Berubicin (RTA 744 free base; WP 744 free base) 是一种 4'-O-苄基阿霉素,具有抗癌活性和血脑屏障透过性。Berubicin 可抑制 P-gp 和 MRP1 介导的外排,抑制多形性胶质母细胞瘤 (GBM),表现出细胞毒性。Berubicin 在小鼠中的生物利用度较差。
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Berubicin
CAS number:677017-23-1 molecular formula:
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| Chinese alias | - | ||
| English alias | - | ||
| CAS number | 677017-23-1 | molecular formula | |
| molecular weight | 633.600 g/mol | Exact mass | - |
| PSA | 195.000 Ų | logp | 3.300 |
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