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Berubicin

CAS number:677017-23-1    molecular formula:

overview

compound introduction

Berubicin (RTA 744 free base; WP 744 free base) 是一种 4'-O-苄基阿霉素,具有抗癌活性和血脑屏障透过性。Berubicin 可抑制 P-gp 和 MRP1 介导的外排,抑制多形性胶质母细胞瘤 (GBM),表现出细胞毒性。Berubicin 在小鼠中的生物利用度较差。

Specs

Chinese alias-
English alias-
CAS number677017-23-1molecular formula
molecular weight633.600 g/molExact mass-
PSA195.000 Ųlogp3.300

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