compound introduction
CP-547632 hydrochloride 是一种口服有效的，ATP 竞争性的 VEGFR-2 和 FGF 激酶抑制剂，IC50 分别为 11 nM 和 9 nM。CP-547632 hydrochloride 对 VEGFR2 和 bFGF 的选择性高于 EGFR，PDGFRβ 和相关的酪氨酸激酶 (TKs)。CP-547632 hydrochloride 具有抗肿瘤作用。
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CP-547632 hydrochloride
CAS number：252003-71-7 molecular formula：C20H25BrClF2N5O3S
overview
Specs
| Chinese alias | - | ||
| English alias | CP-547632 (hydrochloride) | CP-547632 hydrochloride | 3-[(4-Bromo-2,6-difluorophenyl)methoxy]-5-[[[[4-(1-pyrrolidinyl)butyl]amino]carbonyl]amino]-4-isothiazolecarboxamide hydrochloride | AKOS040732862 | UNII-OKR4BWW90F | MS-30286 | CP-547632 hydrochloride | ||
| CAS number | 252003-71-7 | molecular formula | C20H25BrClF2N5O3S |
| molecular weight | 568.86 g/mol | Exact mass | - |
| PSA | 138.000 Ų | logp | - |
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