Information PD089828 is an ATP competitive inhibitor of FGFR-1, PDGFR-β and EGFR with IC50 of 0.15 µM, 1.76 µM, and 5.47 µM, respectively. PD089828 is also a noncompetitive inhibitor of c-Src tyrosine kinase with IC50 of 0.18 µM. PD-089828 inhibits MAPK with IC50 of 7.1 µM.
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PD089828
CAS number:179343-17-0 molecular formula:C18H18Cl2N6O
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| Chinese alias | - | ||
| English alias | - | ||
| CAS number | 179343-17-0 | molecular formula | C18H18Cl2N6O |
| molecular weight | 405.28 g/mol | Exact mass | ≥98% |
| PSA | 106.000 Ų | logp | 3.700 |
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