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BTK inhibitor 1 (Compound 27)

CAS number:2230724-66-8    molecular formula:C24H23FN8O2

overview

compound introduction

Information BTK inhibitor 1 (Compound 27) BTK inhibitor 1 (compound 27) is an inhibitor of BTK with an IC50 of 0.11 nM for Btk and inhibits B cell activation in hWB with an IC50 of 2 nM. Targets BTK (Cell-free assay) 0.11 nM

Specs

Chinese alias-
English alias1,​2,​4-​Oxadiazole-​3-​carboxamide,5-​(1,​1-​dimethylethyl)​-​N-​[[2-​fluoro-​4-​[6-​(1-​methyl-​1H-​pyrazol-​4-​yl)​-​7H-​pyrrolo[2,​3-​d]​pyrimidin-​4-​yl]​phenyl]​methyl]​-
CAS number2230724-66-8molecular formulaC24H23FN8O2
molecular weight474.49 g/molExact mass10mM in DMSO
PSA-logp3.626

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