CAS number：1384071-99-1 molecular formula：C22H19F4N7O
AD80，一种多激酶抑制剂，对人源RET (c-RET)、BRAF、S6K和SRC活性较强，但对mTOR的活性比AD57或AD58弱。其对RET (c-RET)的IC50值为4 nM。 AD80, a multi kinase inhibitor, has strong activity on human RET (c-RET), BRAF, S6K and SRC, but weak activity on mTOR than ad57 or ad58. Its IC50 value for RET (c-RET) is 4 nm.
| Chinese alias | - | ||
| English alias | N-[4-[4-Amino-1-(1-methylethyl)-1H-pyrazolo[3,4-d]pyrimidin-3-yl]phenyl]-N'-[2-fluoro-5-(trifluoromethyl)phenyl]urea | ||
| CAS number | 1384071-99-1 | molecular formula | C22H19F4N7O |
| molecular weight | 473.44 g/mol | Exact mass | ≥99% |
| PSA | 111.000 Ų | logp | 3.700 |
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