CAS number：2130958-55-1 molecular formula：C29H35F3N8O5S
Information Alflutinib (AST2818) mesylate is a third-generationepidermal growth factor receptor (EGFR)inhibitor that inhibits both EGFR-sensitive mutations and T790M mutations. Alflutinib (AST2818), primarily metabolized by CYP3A4, is also a potentCYP3A4inducer with EC50 of 0.25 μM. Targets EGFR ; CYP3A4 (Cell-free assay) ; 0.25 μM(EC50)
| Chinese alias | 甲磺酸艾氟替尼 | ||
| English alias | C29H35F3N8O5S | EX-A2864 | 2130958-55-1 | Furmonertinib mesylate | ALFLUTINIB MESILATE | AC-35567 | Alflutinib mesylate (AST2818 | Alflutinib mesylate | FURMONERTINIB MESILATE | Ivesa | N-(2-((2-(Dimethylamino)ethyl)(methyl)amino)-5-((4-(1-methyl-1H-indol | ||
| CAS number | 2130958-55-1 | molecular formula | C29H35F3N8O5S |
| molecular weight | 664.7 g/mol | Exact mass | ≥98% |
| PSA | 163.000 Ų | logp | 5.192 |
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