CAS number：7415-78-3 molecular formula：C21H24O7
Beta-hydroxyisovalerylshikonin is a natural product isolated from Lithospermum erythrorhizon , acts as a potent inhibitor of protein tyrosine kinases (PTK) , with IC 50 s of 0.7μM and 1μM for EGFR and v-Src receptor, respectively. Beta-hydroxyisovalerylshikonin is effective against a wide variety of tumor cell lines, and most efficiently induces cell-death in NCI-H522 and DMS114 cells Form:Solid IC50& Target:IC50: 0.7 μM (EGFR), 1 μM (v-Src)
| Chinese alias | β-羟基异戊酰紫草素 | ||
| English alias | 3'-Hydroxyisovalerylshikonin; (c)micro-Hydroxyisovalerylshikonin | InChI=1/C21H24O7/c1-11(2)5-8-16(28-17(25)10-21(3,4)27)12-9-15(24)18-13(22)6-7-14(23)19(18)20(12)26/h5-7,9,16,22-23,27H,8,10H2,1-4H3 | NSC110263 | NSC-110263 | beta-Hydroxyisovalerylshikoni | ||
| CAS number | 7415-78-3 | molecular formula | C21H24O7 |
| molecular weight | 388.41 g/mol | Exact mass | ≥99% |
| PSA | 121.000 Ų | logp | 3.400 |
No numbering system information yet
No physical and chemical property information yet
No safety information yet
No production method and use information yet
No upstream information yet
No downstream information yet
