ALK inhibitor 1 (compound 17) is a potent pyrimidin ALK inhibitor. ALK inhibitor 1 is a potent inhibitor of testis-specific serine/threonine kinase 2 ( TSSK2 ; IC 50 =31 nM) and focal adhesion kinase ( FAK ; IC 50 =2 nM). In Vitro ALK inhibitor 1 (compound 17) inhibits IGF-1R with an IC 50 of 90 nM. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid
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ALK inhibitor 1
CAS number:761436-81-1 molecular formula:C23H28BrN7O3S
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| Chinese alias | ALK 抑制剂 1 | ||
| English alias | BCP28167 | AKOS030526894 | SCHEMBL282266 | DTXSID30647725 | 2-((5-Bromo-2-((2-methoxy-4-(4-methylpiperazin-1-yl)phenyl)amino)pyrimidin-4-yl)amino)-N-methylbenzenesulfonamide | HY-15357 | 2-({5-Bromo-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin | ||
| CAS number | 761436-81-1 | molecular formula | C23H28BrN7O3S |
| molecular weight | 562.48 g/mol | Exact mass | ≥99% |
| PSA | 120.000 Ų | logp | 4.100 |
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