Pomalidomide-PEG2-COOH (Pomalidomide 4'-PEG2-acid) 是一种合成的 E3 连接酶配体-linker 偶联物,它包含基于 Pomalidomide 的 cereblon 配体和连接子。Pomalidomide-PEG2-COOH 可用于 PROTAC 合成。
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Pomalidomide-PEG2-COOH
CAS number:2140807-17-4 molecular formula:C20H23N3O8
overview
compound introduction
Specs
| Chinese alias | 3-[2-[2-[[2-(2,6-二氧代-3-哌啶基)-2,3-二氢-1,3-二氧代-1H-异吲哚-4-基]氨基]乙氧基]乙氧基]丙酸 | 泊马度胺-PEG2-COOH | ||
| English alias | 3-[2-[2-[[2-(2,6-Dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]ethoxy]ethoxy]propanoic acid | Pomalidomide-PEG2-CO2H | 3-(2-(2-((2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)ethoxy)ethoxy)propanoic acid | CrosslinkerE3 Li | ||
| CAS number | 2140807-17-4 | molecular formula | C20H23N3O8 |
| molecular weight | 433.42 g/mol | Exact mass | ≥95%(HPLC) |
| PSA | 151.000 Ų | logp | 0.100 |
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MSDS
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2140807-17-4 | Pomalidomide-PEG2-CO2H.pdf





