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Pomalidomide-PEG2-COOH

CAS number:2140807-17-4    molecular formula:C20H23N3O8

overview

compound introduction

Pomalidomide-PEG2-COOH (Pomalidomide 4'-PEG2-acid) 是一种合成的 E3 连接酶配体-linker 偶联物,它包含基于 Pomalidomide 的 cereblon 配体和连接子。Pomalidomide-PEG2-COOH 可用于 PROTAC 合成。

Specs

Chinese alias3-[2-[2-[[2-(2,6-二氧代-3-哌啶基)-2,3-二氢-1,3-二氧代-1H-异吲哚-4-基]氨基]乙氧基]乙氧基]丙酸 | 泊马度胺-PEG2-COOH
English alias3-[2-[2-[[2-(2,6-Dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]ethoxy]ethoxy]propanoic acid | Pomalidomide-PEG2-CO2H | 3-(2-(2-((2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)ethoxy)ethoxy)propanoic acid | CrosslinkerE3 Li
CAS number2140807-17-4molecular formulaC20H23N3O8
molecular weight433.42 g/molExact mass≥95%(HPLC)
PSA151.000 Ųlogp0.100

numbering system

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physicochemical properties

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Safety information

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Production methods and uses

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upstream information

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downstream information

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MSDS

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2140807-17-4 | Pomalidomide-PEG2-CO2H.pdf