Product Application: 1、Applicated in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound. 2、Pomalidomide-PEG2-butyl iodide (CAS No.1835705-72-0) is a crosslinker-E3 ligase ligand conjugate consisting of an E3 ligase ligand pomalidomide and a PEGylated crosslinker with terminal iodoalkane that reacts with the nucleophilic group of the target ligand. It has been used as a degrader building block in PROTAC for targeted protein degradation.
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Pomalidomide-PEG2-butyl iodide
CAS number:1835705-72-0 molecular formula:C23H28IN3O7
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| Chinese alias | 泊马度胺-PEG2-丁基碘 | ||
| English alias | Crosslinker–E3 Ligase ligand conjugate, Partial PROTAC, Pomalidomide-2-2-6-I, N-(2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)-2-(2-((6-iodohexyl)oxy)ethoxy)acetamide, Template for synthesis of targeted protein degrader | ||
| CAS number | 1835705-72-0 | molecular formula | C23H28IN3O7 |
| molecular weight | 585.39 g/mol | Exact mass | ≥95% |
| PSA | - | logp | - |
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1835705-72-0 | Pomalidomide-PEG2-butyl iodide.pdf





