Quasi-orthogonally-protected Lys derivative. The Fmoc group can be removed selectively by treatment with piperidine; the Dde group is cleaved with 2% hydrazine in DMF [1]. When removing Dde in the presence of allyl-based protecting groups, allyl alcohol should be included in the deprotection solution to prevent reduction of the allyl group Quasi-orthogonally-protected Lys derivative. The Fmoc group can be removed selectively by treatment with piperidine; the Dde group is cleaved with 2% hydrazine in DMF [1]. When removing Dde in the presence of allyl-based protecting groups, allyl alcohol should be included in the deprotection solution to prevent reduction of the allyl group
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N^a-1-(4,4-Dimethyl-2,6-dioxocyclohex-1-ylidene)ethyl-N^e-Fmoc-L-lysine
CAS number:156648-40-7 molecular formula:C31H36N2O6
overview
compound introduction
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| Chinese alias | - | ||
| English alias | DS-15038 | L-Lysine, N2-[1-(4,4-dimethyl-2,6-dioxocyclohexylidene)ethyl]-N6-[(9H-fluoren-9-ylmethoxy)carbonyl]- | Dde-Lys(Fmoc)-OH | AKOS015911819 | DTXSID80679793 | (S)-6-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-2-((1-(4,4-dimethyl-2,6-dioxocyclohexyl | ||
| CAS number | 156648-40-7 | molecular formula | C31H36N2O6 |
| molecular weight | 532.6 g/mol | Exact mass | ≥95% |
| PSA | 125.000 Ų | logp | 4.800 |
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MSDS
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156648-40-7 | Dde-Lys(Fmoc)-OH Novabiochem®.pdf





