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N^a-1-(4,4-Dimethyl-2,6-dioxocyclohex-1-ylidene)ethyl-N^e-Fmoc-L-lysine

CAS number:156648-40-7    molecular formula:C31H36N2O6

overview

compound introduction

Quasi-orthogonally-protected Lys derivative. The Fmoc group can be removed selectively by treatment with piperidine; the Dde group is cleaved with 2% hydrazine in DMF [1]. When removing Dde in the presence of allyl-based protecting groups, allyl alcohol should be included in the deprotection solution to prevent reduction of the allyl group Quasi-orthogonally-protected Lys derivative. The Fmoc group can be removed selectively by treatment with piperidine; the Dde group is cleaved with 2% hydrazine in DMF [1]. When removing Dde in the presence of allyl-based protecting groups, allyl alcohol should be included in the deprotection solution to prevent reduction of the allyl group

Specs

Chinese alias-
English aliasDS-15038 | L-Lysine, N2-[1-(4,4-dimethyl-2,6-dioxocyclohexylidene)ethyl]-N6-[(9H-fluoren-9-ylmethoxy)carbonyl]- | Dde-Lys(Fmoc)-OH | AKOS015911819 | DTXSID80679793 | (S)-6-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-2-((1-(4,4-dimethyl-2,6-dioxocyclohexyl
CAS number156648-40-7molecular formulaC31H36N2O6
molecular weight532.6 g/molExact mass≥95%
PSA125.000 Ųlogp4.800

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MSDS

Found 1 shareMSDS
156648-40-7 | Dde-Lys(Fmoc)-OH Novabiochem®.pdf