compound introduction
米卡芬净钠是半合成的环状脂肽米卡芬净的盐，米卡芬净是棘皮菌素类的成员，该物质于1999年在日本藤泽市报道。该钠盐利用了芳基硫酸盐部分，从而提供了改善的水溶性，并且是药物应用中的优选盐。像所有棘手and蛋白一样，米卡芬净抑制β-（1,3）-D-葡聚糖的合成，β-（1,3）-D-葡聚糖是易感真菌细胞壁的重要组成部分。 Micafungin sodium is the salt of the semi-synthetic cyclic lipopeptide, micafungin, a member of the echinocandin class that was reported in 1999 from Fujisawa in Japan. The sodium salt takes advantage of the aryl sulphate moiety providing improved water solubility and is the preferred salt for pharmaceutical applications. Like all echinocandins, micafungin inhibits the synthesis of β-(1,3)-D-glucan, an essential component of the cell wall of susceptible fungi.
